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米非司酮联合甲氨蝶呤保守治疗异位妊娠的疗效观察

黄鑫 李莹莹 纪红 张义楠 沈秀敏

中国药房2011,Vol.22Issue(48):4566-4567,2.
中国药房2011,Vol.22Issue(48):4566-4567,2.

米非司酮联合甲氨蝶呤保守治疗异位妊娠的疗效观察

Efficacy Observation of Mifepristone Combined with Methotrexate Conservative Treatment for Ectopic Pregnancy

黄鑫 1李莹莹 1纪红 1张义楠 1沈秀敏1

作者信息

  • 1. 辽宁医学院附属第一医院妇产科,锦州市121000
  • 折叠

摘要

Abstract

OBJECTIVE: To observe the therapeutic efficacy of mifepristone combined with methotrexate in the treatment of ec-topic pregnancy. METHODS: 243 patients with ectopic pregnancy in our hospital were randomly divided into mifepristone group (121 cases) and mifepristone combined with methotrexate group(122 cases) according to random number table. The length of stay, vaginal bleeding time, the time of β-HCG dropping to normal, the time of mass reduction, abdominal pain, transfer surgery and case number of smooth radiography were observed and recorded. RESULTS: The vaginal bleeding time, the time of β-HCG dropping to normal, the time of mass reduction, case number of abdominal pain in mifepristone combined with methotrexate group were significantly better than mifepristone group (P<0.05). There was no statistical significance in adverse drug reaction and the degree of tubal patency between 2 groups (P>0.05). CONCLUSION: Mifepriston combined with methotrexte in the treatment of ectopic pregnancy has good efficacy and low ADRs.

关键词

异位妊娠/米非司酮/甲氨蝶呤

Key words

Ectopic pregnancy/Mifepristone/Methotrexate

分类

医药卫生

引用本文复制引用

黄鑫,李莹莹,纪红,张义楠,沈秀敏..米非司酮联合甲氨蝶呤保守治疗异位妊娠的疗效观察[J].中国药房,2011,22(48):4566-4567,2.

中国药房

OACSCDCSTPCD

1001-0408

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