摘要
Abstract
OBJECTIVE: To evaluate the therapeutic efficacy and safety of sevoflurane and propofol on maintenance of anesthesia. METHODS: Trials were consulted through electronic searches of the Cochrane library, PubMed database, EMCC database, CHKD database, Sciencedirect database, et al. All randomized-controlled trails of maintenance of anesthesia by sevoflurane and propofol were included into study and quality evaluation and data extraction were all carried out. Meta-analysis was conducted. RESULTS: A total of 21 trials were involved, including 1 090 patients. Results of Meta-analysis showed: there was no statistical difference between sevoflurane and propofol in terms of recovery time[RR= -1.24, 95%CI(- 2.56, 0.08), P=0.07], orientation recovery time[RR=-1.17, 95%CI(-3.56, 1.22), P=0.34], revival time[RR= 1.62, 95%CI(-2.75, 5.99), P=0A7], postoperative agitation[RR= 1.68, 95%CI(0.76, 3.71), P=0.20], postoperative nausea and vomiting[RR= 1.19, 95%CI(0.71, 2.00), P= 0.51]. CONCLUSION: Sevoflurane is similar with propofol in terms of recovery time, orientation recovery time, revival time, postoperative agitation and postoperative nausea and vomiting. High quality large-scale RCTs are required for further study because of low quality of included literatures.关键词
七氟烷/丙泊酚/维持麻醉/系统评价Key words
Sevoflurane/Propofol/Maintenance of anesthesia/Systematic review分类
医药卫生
