中国药房2012，Vol.23Issue(2)：97-101,5.DOI:10.6039/j.issn.1001-0408.2012.02.01
从处方分析探讨“全国抗菌药物临床应用专项整治活动”的必要性
Discussion on the Necessity of “Special Rectification Activities of Clinical Application of Antibacterials in China” through Prescription Analysis
郭澄 1张剑萍 1华雪蔚 2郭丽娜 2万丽丽1
作者信息
- 1. 上海交通大学附属第六人民医院药剂科,上海200233
- 2. 中国医药工业信息中心,上海200040
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the necessity of "Special Rectification Activities of Clinical Application of Antibacteri-als in China". METHODS: The original electronic prescriptions including antibiotics were collected from 9 comprehensive Grade Three hospitals in Shanghai between 2008 and 2010. Excel software was used to summarize all the prescription data, calculating DDDs, compound annual growth rate(CAGR) and antibiotics use density (AUD) , etc. RESULTS: The number of antimicrobial agents' prescriptions and the amount of prescriptions showed a rising trend year by year in the recent 3 years. However, its proportion in the total number and total amount of prescriptions remained stable. Among treatment categories of top 10 drugs in the list of DDDs, the second generation cephalosporins ranked first place and the rising CAGR of DDDs in the 3 years was also the highest. Among the top 10 drugs in the list of DDDs, cephalosporin had four. Cefuroxime (tablets) rose fastest with CAGR of 17.3%. Drugs of restricted use took up the highest proportion of antimicrobials, which was more than 50% ; followed by drugs of non-restricted use with a declining trend year by year. Although the drugs of special use accounted fbr the smallest, they showed a very obvious increasing trend year by year in the three years. The utilization ratio of antimicrobials in hospitalized patients in hospital A among sample hospitals had been above 65% in three years. The AUD of antimicrobials in five key departments were 40.37～ 198.43 DDD/100 persons/ day. There was a large gap with the standard in this special campaigns activity. CONCLUSION: Although the clinical use of antimicrobials has been limited in recent years, antimicrobials abuse remains serious. It needs further efforts of health administrative departments and all levels of medical institutions.关键词
抗菌药物/合理应用/分级管理/抗菌药物使用强度/必要性/处方分析Key words
Antibacterials/Rational use/Management by different grades/Antibiotics use density/Necessity/Prescription analysis分类
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郭澄,张剑萍,华雪蔚,郭丽娜,万丽丽..从处方分析探讨“全国抗菌药物临床应用专项整治活动”的必要性[J].中国药房,2012,23(2):97-101,5.
