中国药房2012，Vol.23Issue(2)：127-129,3.DOI:10.6039/j.issn.1001-0408.2012.02.11
我院2007-2010年鲍曼不动杆菌感染的耐药性分析
Analysis of Antimicrobial Resistance of Acinetobacter baumannii Infection in Our Hospital from 2007 to 2010
摘要
Abstract
OBJECTIVE: To analyze the distribution characteristics and antimicrobial resistance of isolated Acinetobacter baumannii, and to provide reference for rational use of antibiotics in the clinic. METHODS: Microscan WalkAway 40 automatic system (America) was used to identify the species and the minimal inhibitory concentration (MIC) for ,A. Baumannii which were separated from 2007 to 2010. All the data were analyzed by WHONET 5.4 software. RESULTS: A total of 174 strains of A. Baumannii were isolated, which mainly came from the sputum samples of patients(149 strains, 85.6% ). In the distribution of hospital departments, ICU was the most (61 strains, 35.1%), respiratory department was the second (46 strains, 26.4%). 47.7% were older suffers aged more than 60 years (83 strains). A. Baumannii was resistant to 14 kinds of antibiotics increasingly, especially to imipenem, from 17.6% to 64.5%; and we found 88 strains were multidrug-resistant strains, and the relevance ratio was increasing sharply. CONCLUSIONS: Antimicrobial resistance of A. Baumannii and the isolation rate of multidrug-resistant and pandrug-resistant A. Baumannii are increasing year by year. So we must keep an eye on A. Baumannii infection and its drug-resistance changes in order to prevent the emergence and spread of drug-resistant strains.关键词
鲍曼不动杆菌/耐药性/多重耐药和泛耐药菌株Key words
Acinetobacter baumanii/Antimicrobial resistance/Multi-drug resistant and pandrug-resistant strains分类
医药卫生引用本文复制引用
李鑫,郭雷静,张淑芹,陆思静..我院2007-2010年鲍曼不动杆菌感染的耐药性分析[J].中国药房,2012,23(2):127-129,3.基金项目
辽宁省教育厅基金项目(2008402) （2008402）
