摘要
Abstract
OBJECTIVE: To evaluate the effect of L-carnitine on weight reduction systematically. METHODS: According to the requirements of Cochrane systematic review,randomized control trials, which were designed for L-carnitine in the treatment of weight reduction, quality assessment and Meta-analysis were conducted on the inclusion references. RESULTS: The two groups had statistically significant difference in the category of body mass reduction [WMD=2.35, 95%CI(0.35, 4.36) ,P=0.02], BMI decrement [WMD=1.75,95%CI(0.28,3.22),p=0.02], lessening of waist to hip ratio[WMD=0.04,95 %CI( 0.03,0.05) ,P< 0.000 01], body fat decrease[WMD=1.36,95%CI(0.31,2.41) ,P=0.01].There were no statistical significance in the category of skin fold diminution [WMD=0.36,95 % CI (-0.64,1.35), P=0.48] and the total rate of adverse drug reaction[RR=2.00,95 %CI( 0.81,4.91) ,^=0.13]. CONCLUSION: L-carnitine is effective and safe for weight reduction, given that moderate exercise is accompanied for better impact.关键词
左旋肉碱/减肥/系统评价/Meta分析Key words
L-camitine/Weight reduction/Systematic review/Meta-analysis分类
医药卫生
