中国药房2012，Vol.23Issue(6)：558-560,3.DOI:10.6039/j.issn.1001-0408.2012.06.28
国家药品不良反应监测中心发布的《药品不良反应信息通报》简析
Brief Analysis of Adverse Drug Reaction Information Bulletin Issued by National Center for Adverse Drug Reaction Monitoring
陈鸣 1童荣生1
作者信息
- 1. 四川省医学科学院/四川省人民医院药剂科,成都610072
- 折叠
摘要
Abstract
OBJECTIVE: To provide reference for the promotion of rational drug use in the clinic and to avoid the occurrence of some serious adverse drug reactions (ADR) by analyzing the Adverse Drug Reaction Information Bulletin (called Bulletin in short) issued by National Center for Adverse Drug Reaction Monitoring. METHODS: On the basis of the information in Bulletin issued in Jan. 2001~Apr. 2011, the frequency of bulletin issued, the class and dosage forms of involved drugs, the organ or systems involved in ADR, the main clinical manifestations and the reasons of ADRs were analyzed briefly. RESULTS: There were 37 issues of Bulletin issued by National Center for ADR Monitoring from Jan. 2001 to Apr. 2011, in which there were 88 drugs involved including 75 chemical drugs (85.23% ) and 13 Chinese patent medicines (14.77% ); and the largest proportion of chemical drugs were antimicrobial drugs, accounting for 40.00% . The adverse drug reactions induced by injections were nearly equal to those induced by oral preparations. The main clinical manifestations were lesion of skin and its appendants or allergic reactions. Individual differences of patients, irrational drug use and other factors are also the reasons for adverse drug reactions besides drug factors. CONCLUSION: Clinical importance should be attached to ADR monitoring.关键词
药品不良反应/信息通报/国家药品不良反应监测中心/药品不良反应信息通报/分析Key words
Adverse drug reaction/ Information bulletin/ National Center for Adverse Drug Reaction Monitoring/ Adverse Drug Reaction Information Bulletin/ Analysis分类
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陈鸣,童荣生..国家药品不良反应监测中心发布的《药品不良反应信息通报》简析[J].中国药房,2012,23(6):558-560,3.
