中国药房2012，Vol.23Issue(6)：563-565,3.DOI:10.6039/j.issn.1001-0408.2012.06.30
质子泵抑制剂致药品不良反应分析
Analysis of Adverse Drug Reaction Induced by Proton Pump Inhibitors
温晓娜 1刘文生 1郭宏玥 1毛静怡1
作者信息
- 1. 天津市第三中心医院药剂科,天津300170
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the characteristics and regularity of ADR induced by cefixime. METHODS: 10 ce-fixime-induced ADR case reports were collected from domestic medical journals. 79 cefixime-induced ADR cases reported by 3 hospitals during 2000 - 2010 were summarized. A total of 89 ADR cases were analyzed and evaluated. RESULTS: Of total 89 cases of ADR, lesion of skin and appendants took up the biggest proportion (accounting for 41.57% ), followed by nervous system injury (accounting for 19.10%) and digestive system injury (accounting for 15.73%). 48.31% were occurred in children below 10 years old; 46.07% were in sequential therapy. About 38.20% occurred after 48 hours. CONCLUSION: It is necessary to pay attention to ADR induced by cefixime and strengthen observation during medication in order to reduce the serious ADR.关键词
质子泵抑制剂/药品不良反应/分析Key words
Cefixime/ Adverse drue reactions: Analysis分类
医药卫生引用本文复制引用
温晓娜,刘文生,郭宏玥,毛静怡..质子泵抑制剂致药品不良反应分析[J].中国药房,2012,23(6):563-565,3.
