中国真菌学杂志2011，Vol.6Issue(6)：344-349,6.
浅部真菌感染和变态反应性皮肤病相关性研究
Superficial fungal infection and allergic dermatitis
刘芳 1桑红 1胡文星 1孔庆涛 1王雪连 1王高峰 1张敏 1邓德权 1谢其美1
作者信息
- 1. 南京大学医学院临床学院南京军区南京总医院皮肤科,南京210002
- 折叠
摘要
Abstract
Objective To investigate superficial fungal infection in the etiology of allergic dermatitis by comparing the sensitivities of fungal allergens and unfungal allergens among allergic dermatitis patients with or without tinea, and the identification of pathogens. Methods Totally 353 patients with chronic urticaria, eczema or atopic dermatitis were divided into two groups classified by direct microscopic examination; the group with superficial fungal infection ( n =173) and the contra! Group without superficial fungal infection ( n - 180). Skin prick tests were performed in all subjects, but fungal culture were administered only in the patients with superficial fungal infection. Results Positive rates to Trichophyton,Specific Penicillium,Curvularia lunata and Aspergillus fumigatus in experiment group were higher than those in control group ( P ＜ 0. 05). Positive rate to Trichophyton in experiment group was higher than that in control group ( P ＜0.001). There were no statistically significant differences among other fungal allergens and unfungal allergens ( P ＞0.05). T. rubrum (52. 86% ) , T. mentagrophytes (14.18% ) , Epidermophyton floccosum (5. 22% ) and Candida (6. 72% ) were cultured in 134 cases of skin allergic diseases with superficial fungal infection. The positive rates were not statistically significant between Trichophyton and dermatophytes ( P ＞0.05). Conclusions Patients with chronic urticaria or eczema who present immediate hypersensitivity to Trichophyton always have dermatophyte infection. Superficial fungal infections seem to be an important factort in the subjects with chronic urticaria or eczema.关键词
真菌/感染/变态反应性疾病/皮肤Key words
fungus/ infection/ allergic diseases/ skin分类
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刘芳,桑红,胡文星,孔庆涛,王雪连,王高峰,张敏,邓德权,谢其美..浅部真菌感染和变态反应性皮肤病相关性研究[J].中国真菌学杂志,2011,6(6):344-349,6.
