中国中医药信息杂志2012，Vol.19Issue(1)：64-66,3.DOI:10.3969/j.issn.1005-5304.2012.01.024
正交试验法优选防风感冒颗粒制备工艺
Optimization for Preparation Technology of Fangfeng Ganmao Granules by Orthogonal Test Method
刘效栓 1李喜香 1焦正花 1李季文 1王炯 1梁海宁1
作者信息
摘要
Abstract
Objective To optimize the extraction and purification technology of Fangfeng Ganmao Granules. Methods The extraction process was optimized by orthogonal test, with water addition, extraction times and time used for extraction as factors of investigation. In refined process test, alcohol precipitation concentration and the relative density of extract were studied. Each factor had three levels. The baicalin and the yield of dry extract were used as the evaluation indexes. The baicalin was determined by HPLC, and dry extract rates were determined by drying method. Results The best extracting technology condition was as follows: the amount of the water was 8 times of the medicinal materials, the decoction duration was 2 h and for 3 times. The optimum purification process was: alcohol precipitation concentration was 60%, relative density of extract was 1.05 g/mL. Conclusion The optimized process of Fangfeng Ganmao Granules is stable, feasible and convenient. It provides experiment basis for mass production.关键词
正交试验法/防风感冒颗粒/提取工艺Key words
orthogonal test method/ Fangfeng Ganmao Granules/ extraction technology分类
医药卫生引用本文复制引用
刘效栓,李喜香,焦正花,李季文,王炯,梁海宁..正交试验法优选防风感冒颗粒制备工艺[J].中国中医药信息杂志,2012,19(1):64-66,3.
