中国中医药信息杂志2012，Vol.19Issue(3)：13-15,3.DOI:10.3969/j.issn.1005-5304.2012.03.006
陇中消肿止痛合剂预防全髋关节置换术后深静脉血栓的临床研究
Clinical Study of Longzhong Xiaozhongzhitong Mixture on Prevention of Deep Vein Thrombosis after Total Hip Arthroplasty
周明旺 1李盛华 2柳海平 1王承祥 1梁雄勇1
作者信息
- 1. 甘肃省中医院,甘肃,兰州,730050
- 2. 天津中医药大学,天津,300192
- 折叠
摘要
Abstract
Objective To investigate the effect of Longzhong Xiaozhongzhitong mixture on prevention of deep vein thrombosis (DVT) after total hip arthroplasty. Methods A total of 186 patients with artificial total hip arthroplasty were randomly divided into group A (89 cases) and group B (97 cases). After 12 h of surgery, on the basis of rountine measures of preventing DVT, group A received low-molecular-weight heparin calcium (LMWH) 0.6 mL by subcutaneous injection, and group B received Longzhong Xiaozhongzhitong mixture 50 mL orally twice a day for 10 days. The colour Doppler of lower limbs were tested before and after operation, D-dimer was determined at 3, 7, 14 day after operation. The incidence of thrombosis, coagulation parameters, postoperative wound drainage and other changes of the two groups were analyzed. Results There were 9 cases had DVT of lower limbs in two groups (4 cases in group A and 5 cases in group B), 1 case in group B died of pulmonary embolism, 8 cases were cured. The follow-ups of 185 patients averaged 3.4 months. The two groups was similar in the incidence of DVT (P>0.05). The value of FIB and D-dimer in two groups were both decreased respectively than before the treatment (P<0.05). The postoperative drainage volume of group B was less than that of group A (P<0.05). Conclusion Longzhong Xiaozhongzhitong mixture and LMWH therapy are equally effective in the prevention of postoperative DVT.关键词
深静脉血栓/全髋关节置换术/陇中消肿止痛合剂/益气活血化瘀/预防Key words
deep vein thrombosis/ total hip arthroplasty/ Longzhong Xiaozhongzhitong mixture/ supplementing qi and activating blood circulation/ prevention分类
医药卫生引用本文复制引用
周明旺,李盛华,柳海平,王承祥,梁雄勇..陇中消肿止痛合剂预防全髋关节置换术后深静脉血栓的临床研究[J].中国中医药信息杂志,2012,19(3):13-15,3.
