中国卒中杂志2011，Vol.6Issue(12)：960-966,7.
缺血性卒中合并脑白质病变的危险因素研究
Research on the Risk Factors for White Matter Lesions in Ischemic Stroke
摘要
Abstract
Objective To evaluate the situation and risk factors of cerebral white matter lesions in ischemic stroke patients to decrease the prevalence.Methods Four hundred and eighty-three consecutive inpatients from Aug. 2007 to Oct. 2008 with acute ischemic stroke were enrolled into our study that was divided into two groups (with and without white matter lesions). Incidence and risk factors of white matter lesions were evaluated. Logistic regressions were applied to analyze related independent influencing factors. Results Of all the 483 patients, white matter lesions presented in 58.3%, the prevalence and severity of white matter lesions increasing with age(P<0.01). Logistic regression analysis indentified advanced age(OR=1.03, 95%C/ 1.00-1.05, P<0.05), history of hypertension(OR=1.77, 95%CI 1.07-2.91, P<0.05), history of stroke(OR=1.71, 95%CI 1.02-2.88, P<0.05), the level of glucose(OR=1.07, 95%CI 1.00-1.15, P<0.05) and lacunar infarction(OR= 1.89, 95%CI 1.17-3.06, P<0.05) as being significantly and independently associated with presence of white matter lesions. Conclusion The prevalence and severity of white matter lesions increasing with age. The presence of white matter lesions is significantly associated with age, history of hypertention and stroke, the level of glucose and lacunar infarction.关键词
脑梗死/脑白质疏松症/危险因素Key words
Brain infarction/ Leukoariosis/ Risk factors引用本文复制引用
魏娜,沈东超,张玉梅,王春雪,王拥军..缺血性卒中合并脑白质病变的危险因素研究[J].中国卒中杂志,2011,6(12):960-966,7.基金项目
国家自然科学基金项目(81071115)北京市卫生系统高层次卫生技术人才培养计划(2011-3-023) （81071115）
