中华医学杂志（英文版）2012，Vol.125Issue(4)：702-704,3.DOI:10.3760/cma.j.issn.0366-6999.2012.04.026
Newborn screening in Zhejiang, China
Newborn screening in Zhejiang, China
Riziwanguli Maitusong 1Rukeya Japaer 2ZHAO Zheng-yan 1YANG Ru-lai 1HUANG Xiao-lei 1MAO Hua-qing1
作者信息
- 1. Department of Neonatal Screening, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003,China
- 2. School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang 310029, China
- 折叠
摘要
Abstract
Background It has been 11 years since newborn screening started in Zhejiang in 1999.The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.Methods Blood samples were collected from the heels of newborns 72 hours after birth.We have conducted laboratory tests that the congenital hypothyroidism (CH) and circulating levels of thyroid-stimulating hormone (TSH) was detected.Blood phenylalanine (Phe) was detected for phenylketonuria (PKU).Dissociation-enhanced lanthanide fluorescent immunoassay (DELFIA) was used for detection.Results From 1999 to 2009,3875228 newborns were screened and 2309 cases were confirmed as CH and 155 cases were confirmed as PKU.The incidence of CH and PKU were 1:1678 and 1:25 001 respectively.Conclusion In 11 years,the Zhejiang newborn screening center screened more than 3.8 million newboms,and helped more than 2000 CH and PKU patients to obtain early treatment in order to prevent physical disability and mental retardation.关键词
newborn screening/congenital hypothyroidism/phenylketonuriaKey words
newborn screening/congenital hypothyroidism/phenylketonuria引用本文复制引用
Riziwanguli Maitusong,Rukeya Japaer,ZHAO Zheng-yan,YANG Ru-lai,HUANG Xiao-lei,MAO Hua-qing..Newborn screening in Zhejiang, China[J].中华医学杂志（英文版）,2012,125(4):702-704,3.
