中华医学杂志（英文版）2012，Vol.125Issue(5)：747-751,5.DOI:10.3760/cma.j.issn.0366-6999.2012.05.005
Correlation between the survival rate of the patients with synchronous hepatic metastases from gastric carcinoma after surgical resection and patient's index
Correlation between the survival rate of the patients with synchronous hepatic metastases from gastric carcinoma after surgical resection and patient's index
YANG Xin-wei 1LI Zhe 1LIU Kai 1FU Xiao-hui 1YANG Jia-he 1WU Meng-chao1
作者信息
- 1. Department of Laparoscopy, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438,China
- 折叠
摘要
Abstract
Background Many studies have reported the benefit of hepatic resection for solitary and metachronous metastases from gastric cancer.However,indications and surgical results for synchronous hepatic metastases from gastric carcinoma have not been clearly defined.This study was performed to assess the benefits and limits of simultaneous combined resection of both primary gastric cancer and synchronous hepatic metastases,as well as to identify prognostic factors affecting the survival.Methods Between January 2005 and June 2008,13 patients with synchronous hepatic metastases underwent simultaneous combined resection.The clinicopathologic features and the surgical results of the 13 patients were retrospectively analyzed.Patient,tumor (primary and metastatic carcinoma),and operative parameters were analyzed for their influence on survival.Results No patient died and two patients (15.4％) developed complications during peri-operative course.The actuarial 6-month,1-year,and 2-year survival rates after hepatic resection were 76.9％,38.5％,and 30.8％,respectively,and two patients survived for more than 2 years after surgery without any signs of recurrences until latest follow-up.In univariate analysis,hepatic tumor distribution (P=0.01) and number of hepatic metastases (P=0.003) were significant prognostic factors that influenced survival.Factors associated with the primary lesion were not significant prognostic factors.Conclusions Satisfactory survival may be achieved by simultaneous combined resection of both primary gastric cancer and synchronous hepatic metastases in strictly selected patients.The number of hepatic metastases and hepatic tumor distribution are significant prognostic determinants of survival.关键词
synchronous hepatic metastases/gastric carcinoma/surgeryKey words
synchronous hepatic metastases/gastric carcinoma/surgery引用本文复制引用
YANG Xin-wei,LI Zhe,LIU Kai,FU Xiao-hui,YANG Jia-he,WU Meng-chao..Correlation between the survival rate of the patients with synchronous hepatic metastases from gastric carcinoma after surgical resection and patient's index[J].中华医学杂志（英文版）,2012,125(5):747-751,5.
