浙江医学2012,Vol.34Issue(4):274-277,4.
不同年龄多囊卵巢综合征患者中代谢综合征发生情况分析
Prevalence of metabolic syndrome among different age groups of women with polycystic ovary syndrome
摘要
Abstract
To investigate the prevalence of metabolic syndrome (MS Jamong different age groups of womenwith polycystic ovary syndrome (PCOS).Three hundreds and thirty two women with polycystic ovary syndrome weredivided into group A (aged <20y), group B (aged 20-29y) and group C (aged &30y). The prevalence of MS, clinical manifestations, hormonal profile and metabolic abnormalities were compared among groups.ResultsThe prevalence rate of MSin groups A, B and C was 7.69%, 21.45% and 48.39%,respectively (P<0.005). BMI, blood pressure and the rate of acanthosis nigricans did not differ among three groups. The waist circumference and waist-hip rate (WHR) of group C was the highest. The levels of TG (1.58±0.75mmol/L), LDL-C (2.84 ±0.76 mmol/L)and FPG (4.84 ±0.70 mmol/L)of group C were highest, while the level of HDL-C of group C was lowest! P<0.05 Jamong three groups. However, no differences were observed in the levels of total testosterone (T), LH/FSH, 2hPG, fasting insulin (FIN), ISI and HOMA-IR. Among all components of MS, low serum HDL-C was the most common abnormality in all age groups, while high serum glucose was the least common one. The rates of low serum HDL-C and high serum glucose in group C were the highest, and those in group A were the lowest. No differences were found in the prevalence of hypertriglyceridemia and high blood pressure among three age groups.ConclusionPatients with PCOS in elderaged group have a higher prevalence of MS than that of younger group, which may be associated with central obesity, low serum HDL-C and high serum glucose in the elder patients.关键词
年龄/多囊卵巢综合征/代谢综合征Key words
Age/Polycystic ovary syndrome/Metabolic syndrome引用本文复制引用
夏舟岚,华凯,严李萍,丁杰锋..不同年龄多囊卵巢综合征患者中代谢综合征发生情况分析[J].浙江医学,2012,34(4):274-277,4.基金项目
浙江省医药卫生科技计划(2008A157) (2008A157)