质谱学报2011，Vol.32Issue(6)：321-332,12.
液相色谱-串联质谱检测兽药残留中的基质效应研究进展
Progress in Matrix Effect of Veterinary Drug Residues Analysis by High-Performance Liquid Chromatography Tandem Mass Spectrometry
摘要
Abstract
High-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) is a powerful analytical tool which has been applied to a wide variety of studies. One limitation associated with LC-MS/MS analysis is its susceptibility to matrix effect, which should be paid attention. In the present paper, the sources, importance, proposed mechanism, factors, evaluation, eliminating and (or) compensating means of matrix effect in LC-ESI-MS/MS analysis are reviewed, and especially, progress in dealing with matrix effect in typical veterinary drug residues analysis by LC-ESI-MS/MS is summarized.关键词
液相色谱-串联质谱/基质效应/机制/影响因素/兽药残留/消除方法Key words
high-performance liquid chromatography tandem mass spectrometry/matrix effect/ mechanism/ factors/ veterinary drug residues/ elimination分类
化学化工引用本文复制引用
王立琦,贺利民,曾振灵,陈建新..液相色谱-串联质谱检测兽药残留中的基质效应研究进展[J].质谱学报,2011,32(6):321-332,12.基金项目
国家自然科学基金项目(No.31072166)资助 （No.31072166）
