中国中西医结合杂志2012,Vol.32Issue(1):17-19,3.
桂林西瓜霜对宫颈柱状上皮外移患者碱性成纤维细胞生长因子mRNA的影响
Effects of Guilin Watermelon Frost on the mRNA Expressions of Basic Fibroblast Growth Factor in Patients with Uterine Cervical Columnar Ectopy
摘要
Abstract
Objective To study the molecular biological effects of Guilin Watermelon Frost (GWF) on the mRNA expressions of basic fibroblast growth factor (bFGF) in patients with uterine uterine cervical columnar ec-topy. Methods One hundred and sixty patients with uterine cervical columnar ectopy were assigned to two groups by the random digit table. Patients in the treatment group were treated with local spray of GWF, while those in the control group were local applied with bFGF-collagen sponge. The mRNA expressions of bFGF of the uterine tissue were detected in the two groups before and after treatment using RT-PCR. Results Before treatment the mRNA expression of bFGF in the uterine cervical columnar ectopy was 0. 55 ±0.10 in the treatment group and 0.58 ±0.13 in the control group, without insignificant difference (P>0.05). After treatment it significantly increased in the two groups, being 0.82 ±0.17 and 0.78 ±0.15 respectively, showing statistical difference from before treatment (P < 0.01). But no statistical difference existed between the two groups after treatment (P>0. 05). Conclusion GWF showed enhancement on the mRNA expressions of bFGF in patients with uterine cervical columnar ectopy.关键词
桂林西瓜霜/宫颈柱状上皮外移/碱性成纤维细胞生长因子mRNA/RT-PCRKey words
Guilin Watermelon Frost/uterine cervical columnar ectopy/basic fibroblast growth factor mRNA/RT-PCR引用本文复制引用
蒋秋燕,宋金玲,莫海霞,张琪,李艳林,唐乾利..桂林西瓜霜对宫颈柱状上皮外移患者碱性成纤维细胞生长因子mRNA的影响[J].中国中西医结合杂志,2012,32(1):17-19,3.基金项目
国家自然科学基金资助项目(No.30960482) (No.30960482)
广西自然科学基金资助项目(No.2010GXNSFA013207) (No.2010GXNSFA013207)