中国中西医结合杂志2012，Vol.32Issue(2)：168-171,4.
福州地区汉族人群冠心病血瘀证影响因素的病例对照研究
A Case Control Study of Influential Factors for the Han Population with Coronary Heart Disease of Blood Stasis Syndrome in Fuzhou Area
摘要
Abstract
Objective To study main factors and the influencing extent of the susceptibility of the Han population with coronary heart disease (CHD) of blood stasis syndrome (BSS) in Fuzhou area. Methods A case control study was employed in Fujian People's Hospital from August 2009 to January 2010. Patients with recent attack of CHD of BSS and of CHD of non-BSS, as well as patients without CHD of non-BSS were recruited as subjects. Correlated factors with CHD were collected using questionnaire and laboratory examinations. The correlation and the correlation strength between each factor and CHD of BSS were analyzed using one-way and multiple-factor unconditional Logistic regression methods. Results Of the 403 patients in line with inclusion criteria, there were 176 patients with CHD of BSS, 123 with CHD of non-BSS, and 104 without CHD of non-BSS. Results of one-way analysis were reported as follows. Senility, mental labors, hypertension, excessive consumption of oil and salt, depression, stress, past relevant medical history, abnormal prothrombin time (PT), and abnormal hematocrit (HCT) were high-risk factors for CHD of BSS. Regular physical exercise and adequate sleep were protective factors. Except for the effects by age and sex, mental labors, hypertension, excessive consumption of oil and salt, depression, stress, past relevant medical history were still risk factors for CHD of BSS, with the correlation strength (OR value, 95% Cl) being 1.902 (95%CI 1.222 ~2.959), 2.221 (95%CI 1.181 -4.176), 2.945 (95%CI 1.781 -4.871), 1.794 (95%CI 1.114-2.890), 3.462 (95%CI 1.555-7.712), 1.517 (95%CI 1.082-2.128), and 3.159 (95%C11.732~5.764). In the comparison between those with CHD of BBS and those with CHD of non-BBS, excessive consumption of salt and meat, and stress were the risk factors for BSS. After the effects by age and sex were adjusted, the OR value were still 1.586 (95% Cl 1.051 -2.393), 1. 801 (95%CI 1.191 -2.723), and 1. 386 (95%C11.024 -1.876). Conclusions When compared with the population of non-BSS, the predisposing factors for the Han population with CHD of BSS in Fuzhou area covered mental labors, hypertension, excessive consumption of oil and salt, depression, stress, and past relevant medical history. Compared with other syndrome types in Chinese medicine, positive correlation existed between BSS and excessive consumption of salt and meat, as well as stress.关键词
冠心病/血瘀证/影响因素Key words
coronary heart disease/ blood stasis syndrome/ influential factor引用本文复制引用
梅丽娟,熊尚全,王婷,傅小萍,周昆,郑国华..福州地区汉族人群冠心病血瘀证影响因素的病例对照研究[J].中国中西医结合杂志,2012,32(2):168-171,4.基金项目
国家自然科学基金资助项目(No.81072726) （No.81072726）
福建省自然科学基金资助项目(No.2009J01163) （No.2009J01163）
福建中医药大学陈可冀院士基金资助项目(No.CKJ2009003) （No.CKJ2009003）
