中药材2011，Vol.34Issue(11)：1750-1753,4.
阿魏酸的体外神经保护活性研究
Neuroprotective Effect of Ferulic Acid in vitro
摘要
Abstract
Objective:To investigate the neuroprotective effect of ferulic acid on PC12 cells injuries. Methods;With three models of PC12 cells injured by hypoxia,excitatory amino acids(EAA) and radical,the effect of ferulic acid on injured PCI2 cells was observed by MTT assay. Results;Compared with three models,ferulic acid (1 -100 μmol/L) could promote cell viability notably (P< 0.05 or P<0.01). Conclusion;Ferulic acid has notable protective effect on PC12 cells injured by hypoxia,EAA and radical.关键词
阿魏酸/PC12细胞/缺氧损伤/兴奋性氨基酸损伤/自由基损伤Key words
Ferulic acid/PC12 cells/ Hypoxic injury/EAA injury/Radical injury分类
医药卫生引用本文复制引用
罗兰,孙悦..阿魏酸的体外神经保护活性研究[J].中药材,2011,34(11):1750-1753,4.基金项目
国家自然科学基金资助项目(81001600) （81001600）
