中药材2011，Vol.34Issue(11)：1781-1784,4.
附子双酯型生物碱的提取工艺研究
Extraction Technology of Diester-type Alkaloids from Radix Aconiti Lateralis
摘要
Abstract
Objective:To determine the suitable extraction technology of diester-type alkaloids,such as mesaconitine, aconitine and hypaconitine from the roots of Aconitum carmichaeli ( Radix Aconiti lateralis). Methods;The contents of mesaconitine, aconitine and hypaconitine were determined by HPLC. Single-factor experiment was used to study the extraction factors. Results: The suitable extraction technology for diester-type alkaloids was as follows: coarse sizings of Radix Aconiti lateralis was extracted by 10 times ethanol for 3 times (each time for 1 day) at 15°C . The total yield of diester-type alkaloids was 0. 57% , including 0. 16% aconitine, 0. 032% mesaconitine and 0. 38% hypaconitine,and the purity was 18. 81%. Conclusion;The extraction technology is efficient,harmfulless,economical, convenient and can be used for industrial production.关键词
附子/中乌头碱/乌头碱/次乌头碱/提取工艺Key words
Aconitum carmiclweli Debx/Mesaconitine/Aconitine/Hypaconitine/Extraction technology分类
医药卫生引用本文复制引用
刘卓,晏星,徐春霞,侯大斌,袁小红..附子双酯型生物碱的提取工艺研究[J].中药材,2011,34(11):1781-1784,4.基金项目
四川省科技支撑项目(2008SZ0082) （2008SZ0082）
