重庆医学2012，Vol.41Issue(10)：954-955,958,3.DOI:10.3969/j.issn.1671-8348.2012.10.007
强化血糖控制对急性心肌梗死合并应激性高血糖患者的预后影响
Effect of intensive blood glucose control in patients with acute myocardial infarction complicated with hyperglycaemia
贾志 1郭牧 2宋昱 2张云强 2梁海青2
作者信息
- 1. 天津医科大学研究生院,天津,300070
- 2. 泰达国际心血管病医院CCU,天津,300457
- 折叠
摘要
Abstract
Objective To investigate the clinical effectiveness of intensive blood glucose control in acute stage of patients with a-cute myocardial infarction (AMI) complicated with hyperglycaemia. Methods 224 non-diabetic patients with AMI accompanied by hyperglycaemia were randomly divided into 2 groups: conventional treatment group and intensive control group, which respectively received conventional controls and tight controls of blood glucose. The clinical effectiveness was compared between the groups. Results The fasting blood glucose remained reduced at various time points in both groups, however, the intensive control group got lower. Angina and malignant arrhythmia rate in intensive control group were lower than those in conventional treatment group (15.9% vs 27. 4 % , 40. 2% vs 55. 6% ,P = 0. 038 and 0. 021, respectively) , while hypoglycemia rate increased in intensive control group (15. 9% vs 6. 8% ,P = 0. 032). For re-infarction,heart failure,mortality and major adverse cardiac events,no statistical difference was found between the two groups(P>0. 05). During 6 months follow-up period,no statistical diference was found in angina,myocardial infarction,total mortality and re-hospitalization(P>0. 05). Conclusion Hospitalization insuline intensification therapy could raise therapeutic effect on AMI complicated with hyperglycaemia.关键词
心肌梗死/应激性高血糖/胰岛素治疗/预后Key words
acute myocardial infarction/stress hyperglycemia/intensive insulin therap/prognosis引用本文复制引用
贾志,郭牧,宋昱,张云强,梁海青..强化血糖控制对急性心肌梗死合并应激性高血糖患者的预后影响[J].重庆医学,2012,41(10):954-955,958,3.
