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正交试验优选肾炎消白颗粒提取工艺及中试研究

白海玉 韩德强 杨微 王朝宇

江苏大学学报(医学版)2012,Vol.22Issue(2):155-158,4.
江苏大学学报(医学版)2012,Vol.22Issue(2):155-158,4.

正交试验优选肾炎消白颗粒提取工艺及中试研究

Study on orthogonal test and medium enlarge test of extraction process of Shenyanxiaobai granules

白海玉 1韩德强 1杨微 1王朝宇1

作者信息

  • 1. 黑龙江省中医研究院制剂室,黑龙江,哈尔滨,150036
  • 折叠

摘要

Abstract

Objective; To find out the optimum water extraction process for the preparation of Shenyanxi-aobai granules. Methods; During the study orthogonal test was used to find out the optimum extraction process of Shenyanxiaobai granules, with weights of total dissolved solids and Astragaloside IV content taken as targets, then medium enlarge test was studied. Results: The laboratory method determined the extraction process as follows; Eight times of water and extracting 2 h for 3 times, and the inventory rating was 132 g ( 1/10 recipe quantity ). Meanwhile , the optimum extraction process got by medium enlarge test was 8 times of water and extracting for 3 times. The first and second time extracted 1.5 h, and the last time extracted 1 h. The inventory rating was 15. 84. Conclusion; There was difference between the extraction processes de -termined by laboratory study and medium enlarge test.

关键词

肾炎消白颗粒/提取工艺/正交试验/中试

Key words

Shenyanxiaobai granules/extraction process/orthogonal test/medium enlarge test

分类

医药卫生

引用本文复制引用

白海玉,韩德强,杨微,王朝宇..正交试验优选肾炎消白颗粒提取工艺及中试研究[J].江苏大学学报(医学版),2012,22(2):155-158,4.

基金项目

黑龙江省财政厅资助项目(2009-05) (2009-05)

江苏大学学报(医学版)

OACSTPCD

1671-7783

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