临床神经病学杂志2012，Vol.25Issue(1)：8-10,3.
急性脑梗死患者脑组织磁共振波谱研究
Research of magnetic resonance spectrum in patients with acute cerebral infarction
摘要
Abstract
Objective To study the changes of magnetic resonance spectrum ( MRS) in patients with acute cerebral infarction (ACI) in basal ganglia. Methods The levels of N-acetylaspartate (NAA) , choline containing compounds (Cho) , creatine compounds (Cr) , lactate(Lac) and the ratios of NAA/Cr, Cho/Cr were detected by MRS in bilateral basal ganglia in 50 patients with one side of basal ganglia infarction ( ACI group) and 50 patients with other disease (control group). Result In ACI group, the levels of Cho and Cr in lesion side were significantly lower than those in the opposite side (all P < 0. 05 ) , and the levels of NAA, Lac and the ratios of NAA/Cr, Cho/Cr had no significant difference between the two sides. The levels of Cho, NAA and Cr in lesion side and opposite side in ACI group were significantly lower than those in lesion corresponding area in control group ( P < 0. 001 - 0. 05 ) , and the level of Lac was significantly higher (all P <0. 05) . Compared with the lesion corresponding area of control group, the ratio of Cho/Cr in lesion side in ACI group was significantly higher, the ratio of NAA/Cr in the contralateral infarct region was significantly lower ( all P < 0. 05 ) . Conclusion In the acute basal ganglia infarction there is metabolic disorder in the lesion side and opposite side, and which is more seriously in lesion side.关键词
急性脑梗死/磁共振波谱/镜像对比/代谢障碍Key words
acute cerebral infarction/ magnetic resonance spectrum/ image contrast/ metabolic disorder分类
医药卫生引用本文复制引用
黄刚,高幼奇,李明智,张昆南,屈新辉,吴凌峰,谢旭芳,吴晓牧..急性脑梗死患者脑组织磁共振波谱研究[J].临床神经病学杂志,2012,25(1):8-10,3.基金项目
十一五国家科技支撑计划资助项目(2008BAI68B03) （2008BAI68B03）
