临床神经病学杂志2012，Vol.25Issue(1)：66-68,3.
单纤维肌电图对糖尿病周围神经病变的应用价值
Application value of single-fiber electromyography on diabetic peripheral neuropathy
陆强彬 1朱祖福 1彭岚 1王庆广1
作者信息
- 1. 214400 江阴市,东南大学医学院附属江阴医院
- 折叠
摘要
Abstract
Objective To investigate the application value of single-fiber electromyography ( SFEMG) on diabetic peripheral neuropathy ( DPN). Methods The values of jitter and fiber density (FD) of extensor digitorum communis muscle in the dominant side in 129 DPN patients were determined by SFEMG. Nerve conduction velocity (NCS) was performed with the routine method. The abnormal detection rate between SFEMG and NCS were compared. The relationship between the values of jitter, the level of glycosylated hemoglobin ( HbAlC ) and the prognosis were analyzed. Results The abnormal detection rate of SFEMG (91. 5% ) was significantly higher than NCS (78.3%)(P<0.01). The abnormal detection rate of SFEMG in low increasing HbAlC level group (86.4%) was significantly higher than NCS (69.7%) (x2 = 7.69,P<0. 01), and there was no significantly difference in high increasing HbAlC level group. There was a positive correlation between the values of jitter and the level of HbAlC(r = 0. 3132,P <0. 05) . The effective rate (82. 3% ) and cure rate (30. 6% ) in patients with normal or mild abnormal jitter values were significantly higher than the patients with severe abnormal jitter value (54. 2% ,11. 9% ) (χ2 = 11.02,P<0. 01;χ2 = 6.32,P<0.05). Conclusions SFEMG is valuable for the diagnosis, and also can be used for the judgment of DPN prognosis.关键词
单纤维肌电图/糖尿病周围神经病变/颤抖/纤维密度/糖化血红蛋白Key words
single-fiber electromyography/ diabetic peripheral neuropathy/ jitter/ fiber density/ glycosylated hemoglobin分类
医药卫生引用本文复制引用
陆强彬,朱祖福,彭岚,王庆广..单纤维肌电图对糖尿病周围神经病变的应用价值[J].临床神经病学杂志,2012,25(1):66-68,3.
