南京工业大学学报（自然科学版）2012，Vol.34Issue(1)：130-134,5.DOI:10.3969/j.issn.1671-7627.2012.01.028
4种11-脱氧甘草次酸3,30-双糖链皂苷的合成
Synthesis of four 11-deoxoglycyrrhetinic acid 3,30-bisdesmosides
王军 1文伟河 2胡小丽 2朱玉亮2
作者信息
- 1. 江苏警官学院公安科技系,江苏南京210012
- 2. 南京工业大学生物与制药工程学院,江苏南京210009
- 折叠
摘要
Abstract
Four 11 -deoxoglycyrrhetinic acid 3,30-bisdesmosides were synthesized. C3-0H and C30-COOH of 11 -deoxoglycyrrhetinic acid were coupled as glycosyl-receptors with the benzoyl glycoyl trichloroacetimidates through one-pot glycosylation method on the promotion of TMSOTf to afford 11 -deoxoglycyrrhetinic acid 3,30-bisdesmosides (6a, 6b, 6c,6d). The structures were characterized by nuclear magnetic resonance spectroscopy( 1H NMR). The result indicated β glycosidic bond.关键词
11-脱氧甘草次酸/皂苷/糖苷键/合成Key words
11-deoxoglycyrrhetinic acid/ saponin/ glycosidic bond/ synthesis分类
化学化工引用本文复制引用
王军,文伟河,胡小丽,朱玉亮..4种11-脱氧甘草次酸3,30-双糖链皂苷的合成[J].南京工业大学学报（自然科学版）,2012,34(1):130-134,5.
