同济大学学报(医学版)2012,Vol.33Issue(1):96-99,4.DOI:10.3969/j.issn1008-0392.2012.01.021
CIG方案治疗急性髓系白血病疗效分析
Outcome of CIG regiment for treatment of acute myeloid leukemia
魏蓉 1张燕香 1韩颖 1施菊妹1
作者信息
- 1. 同济大学附属第十人民医院血液科上海200072
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and adverse events of CIG regiment (Ara-C, IDA and G-CSF) in treatment of untreated acute myeloid leukemia ( AML) , refractory AML/relapsed AML and elderly AML. Methods CIG regiment was used to treat 36 cmases of acute myeloid leukemia. The outcome was evaluated after 1 cmourse of treatment. The patients for whom treatment has failed were exited from the trial and the responders continued to receive another course of treatment. Patients were followed up, overall survival ( OS) were analyzed. Results For patients with CIG,20 cases achieved completely remission(CR) ,9 cases achieved partial remission (PR) , The total response rate was 80.55%. 14 cases were CR after the first course, 6 cases were CR after the second course. The median OS was 26 months. Conclusion Treatment for previously untreated acute myeloid leukemia (AML) , refractory AML/relapsed AML and eldly AML with CIG regiment is safe and effective.关键词
白血病/髓细胞性/急性/治疗方案Key words
leukemia/ acute/ myeloid/ regiment分类
医药卫生引用本文复制引用
魏蓉,张燕香,韩颖,施菊妹..CIG方案治疗急性髓系白血病疗效分析[J].同济大学学报(医学版),2012,33(1):96-99,4.