石油化工高等学校学报2011，Vol.24Issue(6)：46-49,53,5.DOI:10.3969/j.issn.1006-396X.2011.06.012
“一锅法”合成2,3-二氢-4(1H)-喹唑啉酮衍生物
Efficient “One- Pot” Synthesis of 2,3- Dihydro-4( 1H) - Quinazolinones Derivatives Catalyzed by Aluminum Chloride
摘要
Abstract
2,3 - Dihydro - 4(1H) - quinazolinones derivatives were synthesized efficiently by a three components one-pot reaction of isatoic anhydride, aromatic aldehydes, ammonium salts or primary amines in the presence of aluminum chloride in alcohol-water solution. The structures of products were characterized by IR, 1H - NMR, 13C-NMR, MS techniques and elemental analysis. Compared to the reported methods, this protocol have advantages of short reaction time, high yield, simple experimental and work-up procedures, and environmentally benign procedure.关键词
2,3-二氢-4(1H)-喹唑啉酮/氯化铝/一锅法/多组分反应Key words
2,3-Dihydro-4(1H)-quinazolinones/Alumiunm chloride/One-pot synthesis/Multicomponent reaction分类
能源科技引用本文复制引用
宋志国,王洋,孙啸虎,刘连利,张婷婷..“一锅法”合成2,3-二氢-4(1H)-喹唑啉酮衍生物[J].石油化工高等学校学报,2011,24(6):46-49,53,5.基金项目
辽宁省硅材料工程中心(2009402007) （2009402007）
辽宁省博士科研启动基金资助项目(2009A033) （2009A033）
辽宁省教育厅科学研究资助项目(L2011198). （L2011198）
