生殖医学杂志2012，Vol.21Issue(1)：51-54,4.DOI:10.3969/j.issn.1004-3845.2012.01.013
短期营养不良对雌性小白鼠生殖能力的影响
Correlation between starvation for short period and fertility in female mice
王怀秀 1李弘 1袁彩霞 1秦琴1
作者信息
- 1. 山西省人民医院不孕不育科,太原030012
- 折叠
摘要
Abstract
Objective:To analyze the influence of starvation for short period on fertility of female mice.Methods: Forty female mice were randomized into study group starved for 36 hours and control group with normal diet before oocytes were picked up. The numbers, maturity and the cleavage rate of oocytes retrieved from study group were compared with those from control group. The follicle stimulating hormone (FSH), luteinizing hormone (LH) and estrodiol (E2) levels in both groups were assayed before oocytes were picked up.Results; The numbers of oocytes retrieved were (2. 80±l. 24) in study group and (4. 00±l. 17) in control group. The release rate of first polar body and cleavage rate of oocytes were 12. 5% and 14. 3% in study group, and 88. 8% and 70. 4% in control group respectively. The FSH, LH and Ez levels were (1. 32±0. 49) IU/L, (2. 08±0. 39) IU/L, (13.03±l. 68) pmol/L in study group and (4. 45±0. 72) IU/L, (15. 72±2. 38) IU/L, (133. 69 ± 6. 95) pmol/L in control group respectively. All the parameters between two groups were very significantly different (P<0. 01).Conclusions: In mice, starvation for short period significantly reduced the numbers of oocytes retrieved and adversely affected the maturity and the cleavage rate of oocytes.关键词
小白鼠/营养不良/卵母细胞/体外受精Key words
Mouse/Malnutrition/Oocytes/In vitro fertilization引用本文复制引用
王怀秀,李弘,袁彩霞,秦琴..短期营养不良对雌性小白鼠生殖能力的影响[J].生殖医学杂志,2012,21(1):51-54,4.
