天津中医药2012,Vol.29Issue(1):62-64,3.
手十二井穴剌络放血对一氧化碳中毒昏迷小鼠促醒作用及其机制的初步研究
Effects and mechanisms of stabbing collaterals bloodletting of the hand twelve well points on awaking in coma mice after carbon monoxide poisoning
摘要
Abstract
[Objective] To observe stabbing collaterals bloodletting of the hand twelve well points on awaking in coma mice after carbon monoxide poisoning and discuss the role'of the mechanism of action. [Methods] The 54 Kunming male mice were randomly divided into normal group, model group and treatment group, 18 of each group. Model group and treatment group mice were treated with partial in the tank with static type inhaled the concentration of CO for 4 300 PPM air 60-70 minutes, normal mice didn't give carbon monoxide gas in the tank, empty, time equal with model group. Mice were taking out of tank, the treatment group treated with stabbing collaterals bloodletting of the hand twelve well points. To detect carboxyhemoglobin levels in blood and the state of consciousness immediately, 1 hour and 4 hours after contamination. [Results] Compared with model group, mice coma time significantly shortened in the treatment group. After one hour and four hours, the carboxyhemoglobin concentration in blood in the treatment group of mice was significantly lower than the model group. [Conclusion] Stabbing collaterals bloodletting of the hand twelve well points can improve the state of consciousness and shorten the coma time of mice. The mechanism may be related to reducing blood carboxyhemoglobin concentration of mice.关键词
手十二井穴/刺络放血/一氧化碳中毒/碳氧血红蛋白浓度Key words
twelve-well point of the hand/stabbing collaterals bloodletting/carbon monoxide poisoning/carboxyhemoglobin分类
医药卫生引用本文复制引用
金军,岳颖,屈超超,刘建卫,陈泽林,郭义..手十二井穴剌络放血对一氧化碳中毒昏迷小鼠促醒作用及其机制的初步研究[J].天津中医药,2012,29(1):62-64,3.基金项目
天津市科学技术委员自然科学基金资助项目(08JCYBJC27700). (08JCYBJC27700)