天然产物研究与开发2012，Vol.24Issue(2)：208-211,4.
干酪乳杆菌JH-23中单胺氧化酶抑制剂的初步分离
Separation of Monoamine Oxidase Inhibitor Originated from Lactobacillus casei JH-23
摘要
Abstract
Cell-free extracts derived from Lactobacillus casei JH-23 ,with monoamine oxidase inhibition,were obtained by acetone extraction method. Moreover,four active fractions from extracts were separated by silica thin layer chromatogram, among which the fraction I displayed the strongest monoamine oxidase inhibitory activity,with an inhibitory rate reached 55.4% at concentration of 120 μg/mL. National Center for Drug Screening confirmed that the bioactive fraction was reliably inhibitory to monoamine oxidase and possessed potential anti-ageing effect.关键词
干酪乳杆菌JH-23/单胺氧化酶/丙酮抽提/薄层色谱Key words
lactobacillus casei JH-23/monoamine oxidase/acetone extraction/thin layer chromatogram分类
医药卫生引用本文复制引用
王豪,周凌华,吴正钧,王荫榆,何楚莹,陈卫..干酪乳杆菌JH-23中单胺氧化酶抑制剂的初步分离[J].天然产物研究与开发,2012,24(2):208-211,4.基金项目
国家"十一五"科技支撑计划项目(2006BAD04A14) （2006BAD04A14）
上海市农业成果转化项目(083919n1500) （083919n1500）
