武警医学2012，Vol.23Issue(4)：305-308,4.
丝裂霉素C辅助鼻腔泪囊吻合术治疗泪道阻塞疗效分析
Efficacy of adjunctive use of mitomycin C in dacryocystorhinostomy: a meta-analysis
张社德 1张天峰 2罗荣 1钟秀华1
作者信息
- 1. 730050,兰州,武警甘肃总队医院眼科
- 2. 730050,兰州,武警甘肃总队医院医务处
- 折叠
摘要
Abstract
Objective To evaluale the efficacy and safely of adjunctive use of milomycin C in dacryocyslorhinoslomy Lo LreaL lacrimal passage obslruclion. Methods We searched the Cochrane Library, Embase,PubMed,CBM,CNKI and VIP Lo collect randomized controlled trials ( RCT) of use of mitomycin C in dacryocystorhinostomy. The quality of the included trials was assessed and meta - analyses were conducted by using RevMan 5. 1 software. We conducted subgroup analyses based on the outcome measures and intervention. Results A total of 18 randomized controlled trials involving 1139 eyes were included. There were significant differences in symptom - freedom and patency of the lacrimal drainage system and ostium size of external dacryocystorhinostomy with and without mitomycin C. Although there was no significant difference between the two groups in symptom - freedom and patency of the lacrimal drainage system, the difference was statistically significant in the ostium size of endonasal dacryocystorhinostomy. There were no severe postoperative complications. Conclusions The adjunctive use of mitomycin C improves the efficacy of dacryocystorhinostomy.关键词
丝裂霉素C/鼻腔泪囊吻合术/随机对照试验/Meta分析Key words
mitomycin C/dacryocystorhinostomy/randomized controlled trial/meta - analysis分类
医药卫生引用本文复制引用
张社德,张天峰,罗荣,钟秀华..丝裂霉素C辅助鼻腔泪囊吻合术治疗泪道阻塞疗效分析[J].武警医学,2012,23(4):305-308,4.
