西安交通大学学报（医学版）2012，Vol.33Issue(2)：241-244,4.
檀香不同部位提取物对豚鼠离体肠平滑肌功能的影响
Effects of different sandalwood extracts on isolated ileum smooth muscle of guinea pigs
摘要
Abstract
Objective To conduct an in vitro experiment in different sandalwood extracts obtained with different methods so as to provide pharmacological experiment basis for clarifying the modern characterization that acrid taste can promote circulation of qi. Methods Effects of different sandalwood extracts on the motor function of isolated guinea pig ileum were observed in vitro. Results Conventional sandalwood water-frying liquid, volatile oil and alcohol extract fluid inhibited isolated guinea pig intestine in normal conditions. In contrast, sandalwood water extract fluid could stimulate isolated guinea pig intestine in normal conditions. The four different sandalwood extracts inhibited isolated guinea pig ileum with acetylcholine-caused spasmss sandalwood water extract liquid, volatile oil and alcohol extract liquid inhibited isolated guinea pig ileum with atropine-caused flabby condition, whereas conventional water-frying liquid had no such effect. Conclusion Sandalwood can adjust in two ways the autonomous motion of isolated guinea pig intestine, and exerts an antagonistic action on acetylcholine (Ach)-caused spasm and a synergistic action on atropine-caused flabby condition.关键词
檀香/豚鼠离体肠/乙酰胆碱/阿托品/回肠运动Key words
sandalwood/ isolated guinea pig intestine/ acetylcholine/ atropine/ intestine movement分类
医药卫生引用本文复制引用
刘红艳,郭建生,王小娟,陈君,聂子文,张猛..檀香不同部位提取物对豚鼠离体肠平滑肌功能的影响[J].西安交通大学学报（医学版）,2012,33(2):241-244,4.基金项目
国家科技部973资助项目:中药药性理论相关基础问题研究(No.2007CB512603) （No.2007CB512603）
湖南省中药重点学科基金资助项目 （）
