中国组织工程研究2012，Vol.16Issue(11)：2039-2042,4.DOI:10.3969/j.issn.1673-8225.2012.11.032
骨形态形成蛋白在下颌骨快速牵张成骨中的应用
Application of bone morphogenetic proteins in mandibular fast distraction osteogenesis
摘要
Abstract
BACKGROUND: Distraction osteogenesis has became an effective method in treatment of different kinds of craniofacialdeformities and bone defects. However, the major disadvantage of this method is the long distraction and consolidation period,which may lead to severe complications during the distraction process.OBJECTIVE: To summarize the research progress of the application of bone morphogenetic proteins (BMPs) in fast distractionosteogenesis.METHODS: A computer-based online search in Pubmed database was performed to select the reviews and papers related toBMPs and distraction osteogenesis from 1989 to 2011.RESULTS AND CONCLUSION: A total of 32 literatures on the the application of BMPs in fast distraction osteogenesis wereincluded. BMPs have a strong osteogenic activity and capability of promoting regeneration and remodeling of bone. The presentresearch shows that BMPs can be used to accelerate new bone formation and shorten the treatment period. However, the clinicalapplication of BMPs needs further research.关键词
骨形态形成蛋白/牵张成骨/骨再生/下颌骨/基因治疗分类
医药卫生引用本文复制引用
刘浩,王敏..骨形态形成蛋白在下颌骨快速牵张成骨中的应用[J].中国组织工程研究,2012,16(11):2039-2042,4.基金项目
四川省科技厅公益项目(2008FN0174),原发性高血压与牙槽骨吸收相关性研究. （2008FN0174）
