畜牧与兽医2012，Vol.44Issue(2)：18-21,4.
高铜日粮对生长猪胃底腺Ghrelin分泌的影响
Effects of high dietary copper on ghrelin levels in the fundus gland of growing pigs
摘要
Abstract
The experiment was conducted to examine the effects of dietary copper supplementation on ghrelin mRNA expression levels in the fundus gland of growing pigs. Forty-five cross-bred pigs were randomly assigned to three groups of 15 pigs, each comprising five replicates of 3 animals. Pigs were allocated to diets that contained 5 mg/kg,(as a control) , 125 mg/kg sulphate copper and 125 mg/kg methio-nine copper, respectively. At the end of the experiment five pigs were selected at random from each group, slaughtered and collected the fundus gland for determination of ghrelin mRNA expression levels. The results showed that average daily gain, average daily feed intake, absolute weight and ghrelin expression levels were higher in the pigs fed the diets with 125 mg/kg methionine copper and 125 mg/kg sulphate copper ( P<0. 05 ) , than in the pigs fed the diet with 5 mg/kg copper, Furthermore, gastrin concentration of blood was dramatically higher in the pigs fed the diets with 125 mg/kg methionine copper and 125 mg/kg sulphate copper (P<0. 01) compared to those in 5 mg/kg copper group. The data indicated that high dietary copper appears to increase feed intake and promote weight gain by enhancing ghrelin mRNA expression levels in the fundus gland of pigs. Gastrin secretion might relate to ghrelin gene expression of fundus gland.关键词
铜/胃底腺/Ghrelin/胃泌素/生长猪Key words
copper/ fundus gland/ ghrelin/ gastrin/ growing pigs分类
农业科技引用本文复制引用
杨文艳,杨文杰,高云航,刘国文,杨连玉..高铜日粮对生长猪胃底腺Ghrelin分泌的影响[J].畜牧与兽医,2012,44(2):18-21,4.基金项目
吉林省教育厅资助项目(201045) （201045）
吉林省重大科技攻关项目(09ZDGG008). （09ZDGG008）
