西南国防医药2012,Vol.22Issue(4):367-369,3.DOI:10.3969/j.issn.1004-0188.2012.04.007
尼膜同治疗老年血管性痴呆合并高血压的临床研究
Treatment of senile vascular dementia combined with hypertension with nimotop
王俊 1李运明 2李立宇 3王建1
作者信息
- 1. 610083,成都,成都军区总医院神经内科
- 2. 610083,成都,成都军区总医院质量管理科
- 3. 成都军区联勤部卫生部
- 折叠
摘要
Abstract
Objective To explore the clinical curative effects of oral administration of nimotop on senile vascular dementia complicated with essential hypertension. Methods Senile outpatients with vascular dementia complicated with hypertension were selected. The self - controlled design was used to make comparison of the systolic and the diastolic pressure changes before and after the oral administration of nimotop. The intellectual level and daily living ability of the subjects before and after the medication were evaluated by MMSE and ADL measuring scales. Results Among the subjects with different degrees of essential hypertension, the systolic and the diastolic pressure after the treatment were lower than those before the treatment P < 0. 05 ). After 4 w of administration of nimotop, the scores of MMSE and ADL measuring scales were higher than those before the treatment P < 0. 05 ). Only one patient had transient dizziness within the observation period. Conclusion Nimotop has good curative effects on senile patients with vascular dementia complicated with hypertension. It can significantly improve the patients' cognitive function and daily living ability, and meanwhile reduce the blood pressure with low incidence of adverse reactions.关键词
尼膜同/血管性痴呆/原发性高血压/老年人/MMSE/ADLKey words
nimotop/vascular dementia/essential hypertension/senile people/MMSE/ADL分类
医药卫生引用本文复制引用
王俊,李运明,李立宇,王建..尼膜同治疗老年血管性痴呆合并高血压的临床研究[J].西南国防医药,2012,22(4):367-369,3.