新医学2012，Vol.43Issue(4)：247-249,3.DOI:10.3969/g.issn.0253-9802.2012.04.012
不同分娩方式与乙型肝炎病毒母婴垂直传播关系的研究——附290例分析
Research about the efficacy of delivery mode on maternal-infant transmission of hepatitis B virus
黄柳 1范祎
1季冰 1叶明1
作者信息
- 1. 广州市妇女儿童医疗中心妇产科,510560
- 折叠
摘要
Abstract
Objective; To investigate the efficacy of delivery mode on maternal 4nfant transmission of hepatitis B virus. Methods: According to delivery mode , 290 cases of HBsAg positive mothers were divided into vaginal de -livery group ( n = 168 ) and caesarean section group ( n = 122). Venous blood was drawn from mothers and their neonates, and HBV M was detected by enzyme linked immunoadorbent assay (ELISA). The data were comparedthe difference of infectious rate among the three groups. Results; In 290 patients with HBeAg-positive pregnant women and their newborns , the occurrence of HBV vertical transmission in 26 cases (9. 0% ) of HBV DNA ≤106 , 107~ 1011 and > 1011 copies/L of HBV vertical transmission rates were 3. 8% , 14% , 44% respectively. With increasing HBV DNA levels of HBV vertical transmission increased incidence ( P < 0. 01) . Vaginal delivery group HBV vertical transmission rate was 10. 1% (17/168) , and the cesarean section group HBV vertical transmission rate was 7. 4% (9/122). Two sets of maternal serum HBV DNA ≤1011 copies/L HBV vertical transmission rate were no significant difference ( P > 0. 05 ) , but which was significantly higher incidence of maternal serum HBV DNA > 1011 copies/L HBV vertical transmission of vaginal delivery group cesarean section group (P <0. 05). Conclusion: Caesarean section could decrease the maternal -infant transmission of hepatitis B virus if the HBV DNA is more than 1011 copies/L.关键词
乙型肝炎病毒/母婴垂直传播/分娩方式Key words
Hepatitis B virus/Maternal-infant transmission/Delivery mode引用本文复制引用
黄柳,范祎
,季冰,叶明..不同分娩方式与乙型肝炎病毒母婴垂直传播关系的研究——附290例分析[J].新医学,2012,43(4):247-249,3.
