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HPLC法检测注射用酒石酸吉他霉素中吉他霉素各组分含量

陈欣

湖北医药学院学报2011,Vol.30Issue(6):588-590,3.
湖北医药学院学报2011,Vol.30Issue(6):588-590,3.

HPLC法检测注射用酒石酸吉他霉素中吉他霉素各组分含量

Study on Contents Determination Methodology of Kitasamycinum Composition in Kitasamycin Tartrate for Injection by HPLC

陈欣1

作者信息

  • 1. 广东省药品检验所,广东广州510180
  • 折叠

摘要

Abstract

Objective To develop a HPLC method for determining the contents of kitasamycinum compositions in kitasamycin tartrate for injection. Methods The analysis was performed on a Thermo ODS-2 C18 column( 150 mm x 4. 6 mm,5 p,m). The mobile phase was consisted with 0. 1 mol/L ammonium acetate-methanol-acetonitrile(40' 55: 5) . The detective wavelength was 231 ran. Results The linear range for kitasamycinum composition was from 1.3 to 4.4 mg/Ml( r = 0.9990 to 0. 9998,calculated by kitasamycinum). Conclusion The method was simple,accurate and reproducible.

关键词

注射用酒石酸吉他霉素/吉他霉素组分/高效液相色谱法

Key words

Kitasamycin tartrate for injection/ Kitasamycinum composition/ HPLC

分类

医药卫生

引用本文复制引用

陈欣..HPLC法检测注射用酒石酸吉他霉素中吉他霉素各组分含量[J].湖北医药学院学报,2011,30(6):588-590,3.

湖北医药学院学报

2096-708X

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