诊断学理论与实践2012，Vol.11Issue(1)：78-80,3.DOI:10.3969/j.issn.1671-2870.2012.01.019
骨髓增生异常综合征外周血循环微巨核细胞糖蛋白Ⅱb/Ⅲ a的表达及其临床意义
Expression of gP Ⅱ b/m a on peripheral circulating micromegakaryocytes in myelodysplastic syndrome and its clinical significance
浦杰 1陶英 2杨梅如2
作者信息
- 1. 桂林医学院附属医院血液科,广西桂林541001
- 2. 上海交通大学附属第六人民医院血液科,上海200233
- 折叠
摘要
Abstract
Objective To investigate the expression of gP lib/HI a on peripheral circulating micromeyakaryocytes in patients with myelodysplastic syndrome (MDS) and its clinical significance. Methods Alkaline phosphatase-antialkaline phosphatase (APAAP) immunocytochemical staining technique was used to detect circulating micromegakaryocytes in peripheral blood smears of MDS patients. Results gP II b/Hia positive micromegakaryocyte was found in 65 (74.7%)of the 87 MSD patients examined. Morphologically these cells resemble small lymphocytes and is difficult or impossible to recognize these cells in routinely stained smear. Conclusions The immunocytochemical staining technique is simple and easy to perform. Using immunocytochemical staining method to detect micromegakaryocyte in peripheral blood sample might be helpful for the diagnosis of myelodysplastic syndrome.关键词
骨髓增生异常综合征/微巨核细胞/诊断Key words
Myelodysplastic syndrome/ Micromegakaryocytes/ Diagnosis分类
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浦杰,陶英,杨梅如..骨髓增生异常综合征外周血循环微巨核细胞糖蛋白Ⅱb/Ⅲ a的表达及其临床意义[J].诊断学理论与实践,2012,11(1):78-80,3.
