中国动脉硬化杂志2012，Vol.20Issue(2)：157-160,4.
血液透析患者颈总动脉僵硬度与无症状性脑梗死的相关性
Association of Carotid Arterial Stiffness with Silent Cerebral Infarction in Hemodialysis Patients
周新红 1王海燕 1梁晓萍 1刘晓燕 1丁春艳 1翟蓓1
作者信息
- 1. 中国人民解放军第474医院,新疆乌鲁木齐市830013
- 折叠
摘要
Abstract
Aim To evaluate the association between carotid arterial stiffness and silent cerebral infarction (SCI) in hemodialysis patients. Methods Totally 218 hemodialysis patients in our hospital from January 2006 to January2011 were included in this study. Their clinical and laboratory data were collected. Artherial stiffness index p of common carotid artery was evaluated by an ultrasonic phase-lock Echo-tracking system. Carotid intima media thickness (IMT) was measured by ultrasonography. Carotid plaque score was calculated to quantify the'extent of carotid atherosclerosis ( Cas) using Sutton' methods. Results Pearson' s correlation analysis revealed that artherial stiffness parameter P was positively correlated with age, duration of dialysis, mean IMT, and plaque score (P <0. 05). Stepwise regression analysis revealed that pulse pressure ( p = 0. 501, P < 0. 001 ) and age ( P = 0. 488 , P < 0. 001) were found to be independent determinants of stiffness parameter p, while mean IMT and plaque score as covariates. In addition, stiffness parameter p in patients with SCI was significantly higher than those in patients without SCI ( P < 0. 001) , and yet mean IMT and plaque score had no significant difference in both groups. Conclusion The increased carotid arterial stiffness was associated with the presence of arteriosclerosis and with the presence of SCI in hemodialysis patients.关键词
动脉硬化参数β/内膜中膜厚度/脉压/无症状性脑梗死/血液透析Key words
Stiffness Index (3/ Intima Media Thickness/ Pulse Pressure/ Silent Cerebral Infarction/ Hemo-dialysis分类
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周新红,王海燕,梁晓萍,刘晓燕,丁春艳,翟蓓..血液透析患者颈总动脉僵硬度与无症状性脑梗死的相关性[J].中国动脉硬化杂志,2012,20(2):157-160,4.
