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20-羟二十烷四烯酸在血压及血管舒缩功能中的调节作用

韩冰 赵慧颖

中国动脉硬化杂志2012,Vol.20Issue(2):189-192,4.
中国动脉硬化杂志2012,Vol.20Issue(2):189-192,4.

20-羟二十烷四烯酸在血压及血管舒缩功能中的调节作用

Role of 20-Hydroxyeicosatetraenoic Acid in the Regulation of Blood Pressure and Vasomotor Function

韩冰 1赵慧颖1

作者信息

  • 1. 吉林大学白求恩第一医院心血管疾病诊治中心,吉林省长春市130021
  • 折叠

摘要

Abstract

20-hydroxyeicosatetraenoic acid (20-HETE) is one of the products of cytochrome P-450 (CYP) catalyzing the (o-hydroxyl of arachidonic acid ( AA). With the development of research,it has been discovered that 20-HETE played an important role in the process of organism blood pressure regulation, cerebral blood flow, myocardial contractility and renal function. Furthermore,20-HETE has a close relationship with the occurrence and development of diseases such as tumour, inflammatory function and so on. This article is to summarize the effects of 20-HETE in organism blood pressure and vascular function.

关键词

20-羟二十烷四烯酸/花生四烯酸/细胞色素P450/血压/血管舒缩功能

Key words

20-Hydroxyeicosatetraenoic Acid(20-HETE) / Arachidonic Acid/ Cytochrome P-450/ Vascular Function

分类

医药卫生

引用本文复制引用

韩冰,赵慧颖..20-羟二十烷四烯酸在血压及血管舒缩功能中的调节作用[J].中国动脉硬化杂志,2012,20(2):189-192,4.

中国动脉硬化杂志

OA北大核心CSCDCSTPCD

1007-3949

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