摘要
Abstract
Objective: To explore the treatment effect of basic fibroblast growth factor (bFGF) combined with heparin therapy and red light therapy for deep Ⅱ degree burn wounds. Methods: From February 2008 to March 2011, 135 patients with deep Ⅱ degree burn wounds (181 wounds), according to gender, age, duration, burn area, drug use area, were randomly divided into three groups, which were given conventional treatment (group A), joint heparin treatment (group B), and joint heparin plus red light (group C), respectively. By using SPSS 16. 0 software, the clinical data were analyzed by Student t test, chi-square test and variance analysis. Results: All cases were followed up for 6 - 12 months (9 months on average). The wound healing time in groups A, B and C was (28. 1 + 6. 3), (20. 9 + 4. 5) and (16. 9±3. 9) days respectively (F=ll. 53,P<0. 01). The wound healing rate in groups A, B and C was 70. 1% + 11.3%, 88. 7% + 5. 1%, and 96. 7%+4. 8% respectively (F= 8.24, P<0. 01). The therapeutic effective rate in groups A,B and C was 74. 1%, 90. 4% and 100. 0% respectively (F=8. 95, P< 0. 01). Conclusion: The bFGF combined with heparin and red light therapy can enhance deep Ⅱ degree burn wound healing and shorten the treatment duration.关键词
烫伤创面/肝素/bFGF/红光治疗/创面愈合Key words
Burn wounds/ Heparin/ Basic fibroblast growth factor/ Red light therapy/ Wound healing分类
医药卫生
