中国全科医学2012，Vol.15Issue(3)：262-265,4.
小儿支原体肺炎病情轻重的相关因素研究
Factors Related to the Severity of Symptoms in Children Mycoplasma Pneumoniae Pneumonia
徐哲 1陈华英 1马兵 2石平 2聂永红 3冯德刚 1刘亚军 1文虹 1刘燕1
作者信息
- 1. 628000,四川省广元市中心医院儿科
- 2. 628000,四川省广元市中心医院呼吸内科
- 3. 628000,四川省广元市中心医院放射科
- 折叠
摘要
Abstract
Objective To evaluate factors influencing the severity of MPP. Methods 186 MPP children admitted to Guangyuan Center hospital from 2005 to 2009 were involved into the study. Indirect microparticle agglutinin assay and cold agglu-tinins titer were conducted at both admission and discharge. A total of 186 children with MPP were grouped by age: ^ 2 years of age ( 28 patients ), 3 ~ 5 years of age ( 79 patients ), and ^ 6 years of age ( 79 patients ) . They were also grouped by pneumonia pattern: bronchopneumonia group ( 94 patients ) and segmental/lobar pneumonia group ( 92 patients ) . In addition, the children aged ^ 6 years (79 patients ) were classified into three groups based on the severity of pneumonia: bronchopneumonia group (25 patients), mild segmental/lobar group (31 patients), and severe segmental/lobar group ( 23 patients). Ages, clinical symptoms, pulmonary lesions, laboratory findings and seroconversion rate of the 186 children with MPP were retrospectively analyzed. Results The fever in the three age groups all lasted ^7 days. There were significant differences among the three different age groups in bronchopneumonia, segmental/lobar, white blood cell count, neutrophil, lymphocyte, platelet count and C - reactive protein values ( P <0. 05) . The age, duration of fever, hospitalization, WBC count, neutrophil, lymphocyte, absolute lymphocyte count, platelet count, CRP, ESR and seroconversion rate were significantly different between the bronchopneumonia group and the segmental/lobar group ( P < 0. 05 ) . Hospitalization, CRP and seroconversion rate were significantly different among the bronchopneumonia group, the mild segmental/lobar group and the severe segmental/lobar group ( P < 0. 05 ). Conclusion In MPP, older children had longer fever and more severe pulmonary lesions. The severity of pulmonary lesions was associated with the absence of diagnostic IgM antibodies and lymphocyte count. Rapid pairing IgM serologic test is of great importance for early diagnosis of MPP.关键词
肺炎,支原体/危险因素/年龄因素Key words
Pneumonia, mycoplasma/ Risk factors/ Age factors分类
医药卫生引用本文复制引用
徐哲,陈华英,马兵,石平,聂永红,冯德刚,刘亚军,文虹,刘燕..小儿支原体肺炎病情轻重的相关因素研究[J].中国全科医学,2012,15(3):262-265,4.
