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药物性肝损害患者的循证治疗

宋佳 董卫国 吕晓光 范楷

中国全科医学2012,Vol.15Issue(3):285-288,4.
中国全科医学2012,Vol.15Issue(3):285-288,4.

药物性肝损害患者的循证治疗

Evidence-Based Treatment for A Patient with Drug-Induced Liver Injury

宋佳 1董卫国 1吕晓光 1范楷1

作者信息

  • 1. 430060湖北省武汉市,武汉大学人民医院消化内科
  • 折叠

摘要

Abstract

Objective To draw up an evidence - based treatment for a patient with drug - induced liver injury. Methods Clinical problems were presented on the basis of the patient's conditions, and evidence was collected from the Co-chrane library ( 1970 to 2011 ), PubMed ( 1970 to 2011 ), Embase ( 1970 to 2011 ) and SinoMed database ( 1990 to 2011 ). Reasonable treatment was drawn up on the basis of collected evidence, patient's willingness and the doctor's experience. Results A total of 17 documents were retrieved and involved into the study. The results were analyzed and a treatment plan was formulated , which was stopping using anti - tuberculosis drugs combined with glutathione and diammonium glycyrrhizinate. After a six -month follow up, the plan proved to be optimal. Conclusion Through evidence - based method, individual treatment plan based on solid evidence can obviously improve the efficacy and prognosis of the treatment.

关键词

抗结核药/肝损害/治疗/循证医学

Key words

Antibubercular agents/ Liver injury/ Therapy/ Evidence - based medicine

分类

医药卫生

引用本文复制引用

宋佳,董卫国,吕晓光,范楷..药物性肝损害患者的循证治疗[J].中国全科医学,2012,15(3):285-288,4.

中国全科医学

OA北大核心CSCDCSTPCD

1007-9572

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