中国全科医学2012，Vol.15Issue(12)：1350-1352,3.
奥曲肽联合清蛋白及呋塞米治疗肝肾综合征的临床疗效研究
Octreotide Combined with Albumin and Furosemide in the Treatment of Hepatorenal Syndrome
钟渊斌 1张伦理1
作者信息
- 1. 330006,江西省南昌市,南昌大学第一附属医院感染科
- 折叠
摘要
Abstract
Objective To observe the clinical effect of octreotide combined with albumin and furosemide treatment of hepatorenal syndrome patients. Methods 42 patients with hepatorenal syndrome were randomly divided into two groups. The 19 patients in treatment group were treated with octreotide combined with albumin and furosemide therapy and other comprehensive treatment of liver protection; 23 patients in control group were treated with normal albumin and furosemide, and other comprehensive treatment of liver protection. The clinical effect was compared between the two groups and creatinine, blood urea nitrogen and 24 - hour urine volume changes were observed before and after treatment. Results The levels of creatinine and blood urea nitrogen in treatment group were significantly lower than those in control group, while the 24 - hour urine volume was significantly increased in treatment group than in control group ( P < 0. 05 ) . After treatment, 5 cases were cured, 7 cases were improved and 7 cases were ineffective in treatment group, while 3 cases were cured, 5 cases were improved and 15 cases were ineffective in control group. The difference of clinical effect between the two groups was statistically significant ( P < 0. 05 ) . Conclusion Octreotide combined with albumin and furosemide is an effective method for the treatment of hepatorenal syndrome, which can be improved in terms of reducing the levels of creatinine and blood urea nitrogen and increasing 24 - hour urine volume.关键词
肝肾综合征/奥曲肽/清蛋白/呋塞米/治疗结果Key words
Hepatorenal syndrome/ Octreotide/ Albumin/ Furosemide/ Treatment outcome分类
医药卫生引用本文复制引用
钟渊斌,张伦理..奥曲肽联合清蛋白及呋塞米治疗肝肾综合征的临床疗效研究[J].中国全科医学,2012,15(12):1350-1352,3.
