中国全科医学2012，Vol.15Issue(12)：1356-1359,4.
不同残胃容积胃旁路术对胃癌合并非肥胖型2型糖尿病患者降糖效果的影响
Clinical Study of the Effect of Gastric Bypass with Different Residual Stomach Volume on Non-Obese Patients with Type 2 Diabetes Mellitus
摘要
Abstract
Objective To evaluate the effect of Roux - en - Y gastric bypass with different residual stomach volume on non - obese patients with type 2 diabetes mellitus. Methods From June 2007 to December 2009, 77 non - obese patients with type 2 diabetes mellitus and gastric lesions underwent Roux - en - Y gastric bypass with total gastrectomy ( n = 37 ) or subtotal gastrectomy ( n = 40 ) in the department of general surgery. Patients were observed for twelve months after surgery. The body mass index, the fasting blood glucose and the glycosylated haemoglobin concentrations were retrospectively analyzed before surgery ( 0 month ) and 1, 3 , 6, 12 months after surgery, and the efficiency of the surgery was analyzed 12 months after surgery. Results The body mass index, fasting blood glucose and glycosylated haemoglobin concentrations in the two groups were both significantly decreased after surgery ( P <0. 05 ) . However, no significant differences were found between the two groups at the same time ( P >0. 05 ) .As to the efficiency of the surgery after 12 month, there were also no significant differences between the group of Roux - en - Y gastric bypass with total gastrectomy and the group of Roux - en - Y gastric bypass with subtotal gastrectomy ( P > 0. 05 ) . Conclusion Roux - en - Y gastric bypass surgery can effectively improve glucose metabolism in type 2 diabetic patients, and the therapeutic effect of gastric bypass has no obvious relation to the size of residual stomach volume.关键词
胃旁路术/糖尿病,2型/糖化血红蛋白/血糖/胃容积Key words
Gastric bypass/ Diabetes mellitus, type 2/ Glycosylated haemoglobin/ Blood glucose/ Stomach volume分类
医药卫生引用本文复制引用
林克荣,刘斌,黄盛,王畅,王俊杰,喻敏,王瑜..不同残胃容积胃旁路术对胃癌合并非肥胖型2型糖尿病患者降糖效果的影响[J].中国全科医学,2012,15(12):1356-1359,4.基金项目
福建省重点科技计划项目(2009Y0039) （2009Y0039）
南京军区医药卫生科研重点专项(09Z031) （09Z031）
