中国全科医学2012，Vol.15Issue(13)：1469-1471,3.
血浆同型半胱氨酸水平对原发性高血压患者发生冠心病的预测价值
Prognostic Value of Plasma Homocysteine Level for the Occurrence of Coronary Heart Disease in Patients with Essential Hypertension
孙飞 1马向红 1李广平 1黄群1
作者信息
- 1. 300211天津市,天津医科大学第二医院心脏科
- 折叠
摘要
Abstract
Objective To explore the value of homocysteine ( Hey ) level of patients with essential hypertension in predicting the occurrence of coronary heart disease ( CHD ) . Methods A total of 193 inpatients with essential hypertension undergoing were subdivided as essential hypertension only group ( n = 89 ) and essential hypertension combined with CHD group ( n = 104 ) based on the results of coronary angiography. The prevalence of CHD was analyzed according to the different Hey levels. The logistic regression model was used to determine the risk factors for occurrence of CHD. Results There was a significant difference in levels of Hey and high density lipoprotein - cholesterol between the two groups ( P <0. 01 ). Patients with hyper - homocysteinaemia ( Hhcy ) had a higher morbidity of CHD ( P <0. 05 ). In the logistic regression model, Hhcy was the independent predictor for occurrence of CHD in essential hypertension patients [ OR = 2.260, 95% CI ( 1. 152, 4.435 ), P < 0. 05 ] . Conclusion Hyperhomocysteinaemia has the prognostic value for the occurrence of CHD in patients with essential hypertension.关键词
高血压/冠心病/高同型半胱氨酸血症/同型半胱氨酸/危险因素Key words
Hypertension/Coronary disease/Hyperhomocysteinaemia/Homocysteine/Risk factors分类
医药卫生引用本文复制引用
孙飞,马向红,李广平,黄群..血浆同型半胱氨酸水平对原发性高血压患者发生冠心病的预测价值[J].中国全科医学,2012,15(13):1469-1471,3.
