中国全科医学2012，Vol.15Issue(15)：1671-1673,1676,4.
阻塞性睡眠呼吸暂停低通气综合征患者的认知功能特点及影响因素研究
Study on Cognitive Function of Patients with Obstructive Sleep Apnea Hypopnea Syndrome and Its Influencing Factors
摘要
Abstract
Objective To study the cognitive function features of patients with obstructive sleep apnea hypopnea syn -drome (OSAHS) and influencing factors through modified Chinese version of Montreal Cognitive assessment (MoCA). Methods46 OSAHS patients and 44 healthy subjects were involved into the study. The differences of abnormal ratio , total score and each item score of MoCA between the two groups were compared. The influencing factors of cognitive function including variation of sleep mode, apnea -hypopnea index (AHI) , the lowest and mean oxygen saturation and education level were analyzed. ResultsThe MoCA abnormality rate of OSAHS group (47. 82% ) showed statistically significant difference compared with that of the control group (8. 69% ) (P <0.05 ). The MoCA total score of OSAHS group also showed statistically significant difference com -pared with control group (P < 0. 05 ) . Patients in OSAHS group showed significant damage in clock drawing test and delayed memory with increased arousal index and reduced sleep efficiency. AHI was negatively correlated with the lowest and mean oxygen saturation. Education level was positively correlated with MoCA total score. Conclusion Cognitive decline in patients with OSAHS may relate to repeated hypoxemia and sleep disorder. Education level is one of the key factors influencing the results of MoCA.关键词
睡眠呼吸暂停综合征/蒙特利尔认知量表/认知障碍Key words
Sleep apnea syndromes/Montreal cognitive assessment/Cognition disorders分类
医药卫生引用本文复制引用
李振华,承欧梅,李增友,晏勇,晏宁,彭竹芸,韩宇,吴秀书..阻塞性睡眠呼吸暂停低通气综合征患者的认知功能特点及影响因素研究[J].中国全科医学,2012,15(15):1671-1673,1676,4.基金项目
重庆市自然科学基金项目(CSTC,2010BB5110) （CSTC,2010BB5110）
