中国全科医学2012，Vol.15Issue(15)：1695-1697,3.
降钙素原和C反应蛋白对老年人下呼吸道感染病情严重程度及预后评估的价值
Value of Procalcitonin and C-Reactive Protein in Assessing the Severity and Prognosis of Elderly Patients with Lower Respiratory Tract Infection
王敏 1郑世良 2程善光3
作者信息
- 1. 261031山东省潍坊市,潍坊医学院附属医院急诊科
- 2. 261031山东省潍坊市,潍坊医学院附属医院呼吸科
- 3. 261031山东省潍坊市,潍坊医学院附属医院设备科
- 折叠
摘要
Abstract
Objective To evaluate the value of procalcitonin (PCT) and C - reactive protein (CRP) in assessing the severity and prognosis of elderly patients with lower respiratory tract infection. Methods 95 elderly patients with lower respirato -ry tract infection ( case group ) and 30 healthy people ( control group ) were involved into the study. PCT and CRP were detected , and the incidence of respiratory failure and hospital stays were observed. Results The levels of serum PCT and CRP in case group were significantly higher than those in control group (P <0. 01). The levels of serum PCT and CRP were significantly in -creased when comparing moderate group with mild group , severe group with moderate group and severe group with mild group (P < 0.05 ). Serum PCT was positively correlated with CRP and serum PCT and CRP were positively correlated with the severity of the disease. The levels of serum PCT and CRP in patients with respiratory failure were significantly higher than those in patients without respiratory failure (P <0. 01). When taking PCT > 1. 5 μg/L as critical value, 85 elderly patients with lower respiratory tract infection had increased serum PCT , and their hospital stays (13. 39 ± 13. 82 ) d were significantly longer than those without increased serum PCT (9. 06 ± 8. 67 ) d (t = 2. 45 , P < 0. 01). When taking CRP > 10 mg/L as critical value, 79 elderly pa-tients with lower respiratory tract infection had increased serum CRP , and their hospital stays ( 13. 87 ± 12. 06 ) d were signifi-cantly longer than those without increased serum CRP (9. 15 ±8.24) d(t=2. 86, P <0. 01). Conclusion Combined detec-tion of serum PCT and CRP in elderly patients with lower respiratory tract infection can reflect the severity of the disease and is valuable in assessing prognosis , providing theoretical evidence for correct use of antibiotics.关键词
呼吸道感染/老年人/C反应蛋白质/降钙素原Key words
Respiratory tract infections/Aged/C - reactive protein/Procalcitonin分类
医药卫生引用本文复制引用
王敏,郑世良,程善光..降钙素原和C反应蛋白对老年人下呼吸道感染病情严重程度及预后评估的价值[J].中国全科医学,2012,15(15):1695-1697,3.
