中国全科医学2012，Vol.15Issue(15)：1756-1758,3.
经直肠高强度聚焦超声治疗局限性前列腺癌的疗效分析
Transrectal High-Intensity Focused Ultrasound in the Treatment of Localized Prostate Cancer
童亮 1吕军 2沈文 2王尉 2淡明江 2吴浩明 2胡卫列 2徐文峰3
作者信息
- 1. 510515广东省广州市,南方医科大学广州军区广州总医院泌尿外科
- 2. 广州军区广州总医院泌尿外科
- 3. 佛山市第一人民医院泌尿外科
- 折叠
摘要
Abstract
Objective To evaluate the efficacy of transrectal high -intensity focused ultrasound (HIFU) therapy in the treatment of patients with localized prostate cancer. Methods 85 localized prostate cancer patients admitted to our hospital from December 2002 to October 2009 were divided into lower risk group , intermediate risk group and high risk group. Sonablate 500 was used to perform transrectal HIFU local treatment. Prostate special antigen (PSA) and prostate biopsy negative rate were dynamically observed after operation. Results The levels of PSA were significantly decreased three months , six months and twelve months after operation compared with before operation (P <0. 01 ).66 patients (77. 6% ) had PSA nadir≤0. 5 μg/L, and two -year biochemical free survival rate (BFSR) was 57. 8% (48/83). The prostate biopsy negative rate was 72. 9% (62/ 85) and 51. 8% (43/83) respectively six months and twelve months after operation. Conclusion This study shows that HIFU can achieve good efficacy for low risk and intermediate risk localized prostate cancer , especially for low risk group. But for high risk prostate cancer, HIFU monotherapy cannot achieve satisfactory result.关键词
超声,高强聚焦,经肠/前列腺肿瘤/治疗Key words
Ultrasound high - intensity focused transrectal/Prostatic neoplasms/Therapy分类
医药卫生引用本文复制引用
童亮,吕军,沈文,王尉,淡明江,吴浩明,胡卫列,徐文峰..经直肠高强度聚焦超声治疗局限性前列腺癌的疗效分析[J].中国全科医学,2012,15(15):1756-1758,3.
