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首页|期刊导航|中国神经再生研究(英文版)|The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system

The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system

Maoguang Yang Xiaoyu Yang Minfei Wu Peng Xia Chunxin Wang Peng Yan Qi Gao Jian Liu Haitao Wang Xingwei Duan

中国神经再生研究(英文版)2012,Vol.7Issue(11):842-848,7.
中国神经再生研究(英文版)2012,Vol.7Issue(11):842-848,7.DOI:10.3969/j.issn.1673-5374.2012.11.008

The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system

The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system

Maoguang Yang 1Xiaoyu Yang 1Minfei Wu 1Peng Xia 1Chunxin Wang 1Peng Yan 1Qi Gao 1Jian Liu 1Haitao Wang 1Xingwei Duan1

作者信息

  • 1. Department of Orthopedics, China-Japan Union Hospital, Jilin University, Changchun 130033, Jilin Province, China
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摘要

Abstract

In this review, we discuss the role of microtubule-associated protein 1B (MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system. MAP1B exhibits similar functions during axonal development and regeneration. MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components, and regulate the stability and interaction of microtubules and actin to promote axonal growth, neural connectivity and regeneration in the central nervous system.

关键词

microtubule-associated protein 1B/central nervous system/axonal regeneration/axonal development/axon guidance/neuronal migration

Key words

microtubule-associated protein 1B/central nervous system/axonal regeneration/axonal development/axon guidance/neuronal migration

引用本文复制引用

Maoguang Yang,Xiaoyu Yang ,Minfei Wu,Peng Xia,Chunxin Wang,Peng Yan,Qi Gao,Jian Liu,Haitao Wang,Xingwei Duan..The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system[J].中国神经再生研究(英文版),2012,7(11):842-848,7.

基金项目

This work was supported by the National Natural Science Foundation of China (Establishment of corticospinal tract ischemic injury model in goat and axonal guidance of microtubule-associated protein 1B in bone marrow-derived mesenchymal stem cells migratio ()

中国神经再生研究(英文版)

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1673-5374

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