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Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning

Yanhong Luo Yaodong Wei Taizhong Wang Dongzhu Chen Tiansheng Lu Ruibo Wu Keke Si

中国神经再生研究(英文版)2012,Vol.7Issue(12):896-899,4.
中国神经再生研究(英文版)2012,Vol.7Issue(12):896-899,4.DOI:10.3969/j.issn.1673-5374.2012.12.003

Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning

Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning

Yanhong Luo 1Yaodong Wei 2Taizhong Wang 1Dongzhu Chen 3Tiansheng Lu 3Ruibo Wu 3Keke Si3

作者信息

  • 1. Department of Clinical Biochemistry and Molecular Biology, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
  • 2. Department of Biochemistry and Molecular Biology, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
  • 3. Grade 2008, Department of Medical Laboratory Science, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
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摘要

Abstract

Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immuno-sorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.

关键词

pine pollen/arsenic poisoning/apoptosis/cerebral cortex/neural regeneration

Key words

pine pollen/arsenic poisoning/apoptosis/cerebral cortex/neural regeneration

引用本文复制引用

Yanhong Luo,Yaodong Wei,Taizhong Wang,Dongzhu Chen,Tiansheng Lu,Ruibo Wu,Keke Si..Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning[J].中国神经再生研究(英文版),2012,7(12):896-899,4.

基金项目

This study was supported by the Guangxi Bureau of Traditional Chinese Medicine,No.[2009]73 ()

the Department of Science and Technology,Guangxi Zhuang Autonomous Region, No.0640203. ()

中国神经再生研究(英文版)

OACSCDCSTPCDSCI

1673-5374

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